I just found out that Valerian root is a GABA agonist and also can cause rebound anxiety and insomnia - making it physically addictive. We need to start adding that into the argument for keeping kratom legal. if kratom is demonized for sharing opioid qualities, valerian should be satanized for sharing qualities with the even more dangerous benzodiazapine family. How to Mix Kratom and Valerian Root. The first thing you need to consider before mixing kratom and valerian root is the dosage. Both valerian root and kratom have relaxing effects that in high doses can be sedative. Therefore, in order to avoid drowsiness and sedation, it is better to consume moderate doses of both products. Also, kratom. Is Kratom illegal in your jurisdiction? Valerian is a good Kratom alternative to Mitragyna Specioca and is legal in most parts of the world. Valerian is an herb. It is native to E In Henningfield's 127 page report he suggested that kratom should be regulated as a natural supplement, such as St. Johns Wort or Valerian, under the FDA's Food, Drug and Cosmetic Act. The American Kratom Association then submitted this report to the DEA during the public comment period. I use 10g of kratom/day, and I take 3 capsules of valerian root probaly 2-3 times a week. no adverse effects Valerian root stimulates the production of the CYP2D6 enzyme that unlocks kratom’s effects. Valerian root has long been used as a natural supplement for sleep disorders and chronic conditions like Fibromyalgia. For these reasons, valerian root is believed to be a natural pain reliever which can make a valerian-kratom combo a viable option. Valerian Root: popular as a herbal component, this root has supplements commonly available in the market. They are mainly used for peaceful sleep and relaxation. Kratom and Valerian root supplement can go well together for the stress release, sedation, and euphoria. Kratom and Valerian root. Valerian root is widely used as a sleep aid and for its sedative and anxiolytic effects. Kratom and Valerian root taken together lead to a more mellow and relaxing effect, making the combination very effective in treating anxiety and insomnia. To potentiate kratom, you need to induce CYP2D6 (the same enzyme seems to also help potentiate elemicin). If you are low in CYP2D6 kratom will have almost no effects (just like elemicin). The only herb I know of that’s said to induce CYP2D6 is Valerian. Valerian root essential oil is the best bet (about 3 drops or so). Although I've never used kratom, I take valerian root on a semi-regular basis to help with my insomnia.When I initially investigated which form of it to take, I recall reading that the teas and pills/capsules are slower to work, but will sedate you eventually.